The N3 is expected to open later today after the Van Reenen Pass was closed to all traffic this morning (Tuesday) when two trucks collided.
Anita Heyl, spokeswoman for N3 Toll Concession, said that traffic had been stopped at the Tugela Toll Plaza in KwaZulu-Natal and that traffic was backed up near Harrismith in the Free State.
There were no reports of injuries or fatalities from the accident scene.